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  1. This paper describes a project led by the University of South Carolina (USC) to address the cybersecurity workforce gap. The project creates curricular material based on virtual laboratories (vLabs). As vLabs are developed, they are adopted and tested at USC and Northern New Mexico College (NNMC), the main partnering institution in this project. These vLabs consist of virtual equipment (e.g., virtual network, virtual router, virtual firewall) emulating complete systems on-demand running in NETLAB. NETLAB is a widely used platform for training purposes across the country, with more than 1,000 institutions currently using it. USC and NNMC have also established an alliance with industry organizations and with Los Alamos National Laboratory (LANL) and Savannah River National Laboratory (SRNL) to establish internship opportunities. Currently, student interns are not only exercising technical skills but also developing soft skills such as team work and time management. Finally, in partnership with manufacturer leaders, the project permits students to earn industry certificates. These certificates are aligned with the guidelines for “Information Technology Curricula 2017 for IT programs” by the IEEE/ACM. Specifically, the guidelines indicate that IT should emphasize “learning IT core concepts combined with authentic practice” and “use of professional tools and platforms.” Hands-on vLabs activities show that providing access to computing technologies (e.g., professional next-generation firewalls, routers) used in the work environment eases the transition of students from academia to the workplace. 
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  2. This paper describes a project led by the University of South Carolina (USC) to address the cybersecurity workforce gap. The project creates curricular material based on virtual laboratories (vLabs). As vLabs are developed, they are adopted and tested at USC and Northern New Mexico College (NNMC), the main partnering institution in this project. These vLabs consist of virtual equipment (e.g., virtual network, virtual router, virtual firewall) emulating complete systems on-demand running in NETLAB. NETLAB is a widely used platform for training purposes across the country, with more than 1,000 institutions currently using it. USC and NNMC have also established an alliance with industry organizations and with Los Alamos National Laboratory (LANL) and Savannah River National Laboratory (SRNL) to establish internship opportunities. Currently, student interns are not only exercising technical skills but also developing soft skills such as team work and time management. Finally, in partnership with manufacturer leaders, the project permits students to earn industry certificates. These certificates are aligned with the guidelines for “Information Technology Curricula 2017 for IT programs” by the IEEE/ACM. Specifically, the guidelines indicate that IT should emphasize “learning IT core concepts combined with authentic practice” and “use of professional tools and platforms.” Hands-on vLabs activities show that providing access to computing technologies (e.g., professional next-generation firewalls, routers) used in the work environment eases the transition of students from academia to the workplace. 
    more » « less
  3. This paper describes a project led by the University of South Carolina (USC) to address the cybersecurity workforce gap. The project creates curricular material based on virtual laboratories (vLabs). As vLabs are developed, they are adopted and tested at USC and Northern New Mexico College (NNMC), the main partnering institution in this project. These vLabs consist of virtual equipment (e.g., virtual network, virtual router, virtual firewall) emulating complete systems on-demand running in NETLAB. NETLAB is a widely used platform for training purposes across the country, with more than 1,000 institutions currently using it. USC and NNMC have also established an alliance with industry organizations and with Los Alamos National Laboratory (LANL) and Savannah River National Laboratory (SRNL) to establish internship opportunities. Currently, student interns are not only exercising technical skills but also developing soft skills such as team work and time management. Finally, in partnership with manufacturer leaders, the project permits students to earn industry certificates. These certificates are aligned with the guidelines for “Information Technology Curricula 2017 for IT programs” by the IEEE/ACM. Specifically, the guidelines indicate that IT should emphasize “learning IT core concepts combined with authentic practice” and “use of professional tools and platforms.” Hands-on vLabs activities show that providing access to computing technologies (e.g., professional next-generation firewalls, routers) used in the work environment eases the transition of students from academia to the workplace. 
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  4. Abstract

    Oxime antidotes regenerate organophosphate‐inhibited acetylcholinesterase (AChE). Although they share a common mechanism of AChE reactivation, the rate and amount of oxime that enters the brain are critical to the efficacy, a process linked to the oxime structure and charge. Using a platform based on the organophosphate [18F]‐VXS as a positron emission tomography tracer for active AChE, thein vivodistribution of [18F]‐VXS was evaluated after an LD50dose (250 μg/kg) of the organophosphate paraoxon (POX) and following oximes as antidotes. Rats given [18F]‐VXS tracer alone had significantly higher radioactivity (two‐ to threefold) in the heart and lung than rats given LD50POX at 20 or 60 min prior to [18F]‐VXS. When rats were given LD50POX followed by 2‐PAM (cationic), RS194b (ionizable), or monoisonitrosoacetone (MINA) (neutral), central nervous system (CNS) radioactivity returned to levels at or above untreated naive rats (no POX), whereas CNS radioactivity did not increase in rats given the dication oximes HI‐6 or MMB‐4. MINA showed a significant, pairwise increase in CNS brain radioactivity compared with POX‐treated rats. This newin vivodynamic platform using [18F]‐VXS tracer measures and quantifies peripheral and CNS relative changes in AChE availability after POX exposure and is suitable for comparing oxime delivery and AChE reactivation in rats.

     
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